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折扣/货期| 货号：450-35-100UG | 规格：100 ug | 目录价：￥13295 |
| 货号：450-35-1MG | 规格：1 mg | 目录价：￥53305 |
| 货号：450-35-20UG | 规格：20 ug | 目录价：￥2956 |
| 货号：450-35-250UG | 规格：250 ug | 目录价：￥23263 |
| 货号：450-35-500UG | 规格：500 ug | 目录价：￥34575 |
| 货号：450-35-5UG | 规格：5 ug | 目录价：￥1213 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Murine Persephin
别名:
PSP, PSPN
产品描述:
Persephin is a disulfide-linked, homodimeric, neurotrophic factor structurally related to GDNF, artemin, and neurturin. These proteins belong to the cysteine knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. The GFRalpha4 was first identified in chicken, and was later shown to be the preferential binding subunit for persephin. Persephin promotes the survival of ventral midbrain dopaminergic neurons and motor neurons after sciatic nerve oxotomy, and, like GDNF, promotes ureteric bud branching. However, in contrast to GDNF and neurturin, persephin does not support the survival of peripheral neurons. Recombinant Murine Persephin is a disulfide-linked homodimer, composed of two 10.3 kDa polypeptide chains (192 total amino acid residues). Each chain contains seven conserved cysteine residues, one of which (Cys 63) is used for inter-chain disulfide bridging, and the others are involved in the intramolecular ring formation known as the cysteine-knot configuration.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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