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折扣/货期| 货号：217-17RA-10UG | 规格：10 ug | 目录价：￥1195 |
| 货号：217-17RA-50UG | 规格：50 ug | 目录价：￥2974 |
| 货号：217-17RA-100UG | 规格：100 ug | 目录价：￥7123 |
| 货号：217-17RA-250UG | 规格：250 ug | 目录价：￥13754 |
| 货号：217-17RA-500UG | 规格：500 ug | 目录价：￥20447 |
| 货号：217-17RA-1MG | 规格：1 mg | 目录价：￥31519 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Murine sIL-7 Receptor Alpha
别名:
IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127
产品描述:
CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. CD127 consists of an alpha chain and a gamma chain. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency. Recombinant Murine sIL-7 Receptor α Fc is a 51.0 kDa protein containing 452 amino acid residues consisting of the extracellular domain of the mature sequence, as well as a 230 C-terminal Fc region linked by two glycines. As a result of glycosylation, the Recombinant Murine sIL-7 Receptor α Fc migrates as a diffused band to an apparent molecular weight of approximately 65-75 kDa, under reducing conditions.
宿主来源:
CHO cells
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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