Recombinant Murine sIL-7 Receptor Alpha-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

首页产品中心细胞因子、趋化因子与生长因子

Recombinant Murine sIL-7 Receptor Alpha

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：217-17RA-10UG	规格：10 ug	目录价：￥1189
货号：217-17RA-50UG	规格：50 ug	目录价：￥2959
货号：217-17RA-100UG	规格：100 ug	目录价：￥7088
货号：217-17RA-250UG	规格：250 ug	目录价：￥13686
货号：217-17RA-500UG	规格：500 ug	目录价：￥20345
货号：217-17RA-1MG	规格：1 mg	目录价：￥31362

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Murine sIL-7 Receptor Alpha

别名:

IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127

产品描述:

CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. CD127 consists of an alpha chain and a gamma chain. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency. Recombinant Murine sIL-7 Receptor α Fc is a 51.0 kDa protein containing 452 amino acid residues consisting of the extracellular domain of the mature sequence, as well as a 230 C-terminal Fc region linked by two glycines. As a result of glycosylation, the Recombinant Murine sIL-7 Receptor α Fc migrates as a diffused band to an apparent molecular weight of approximately 65-75 kDa, under reducing conditions.

宿主来源:

CHO cells

保存温度:

Minus 20C

运输温度:

Room Temperature

预期分子量:

产品形式:

Standard

产地:

美国

Accession #: