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折扣/货期| 货号：400-30-100UG | 规格：100 ug | 目录价：￥23072 |
| 货号：400-30-10UG | 规格：10 ug | 目录价：￥2956 |
| 货号：400-30-1MG | 规格：1 mg | 目录价：￥92394 |
| 货号：400-30-250UG | 规格：250 ug | 目录价：￥40345 |
| 货号：400-30-2UG | 规格：2 ug | 目录价：￥1213 |
| 货号：400-30-500UG | 规格：500 ug | 目录价：￥59940 |
| 货号：400-30-50UG | 规格：50 ug | 目录价：￥13828 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Rat sRANK Ligand
别名:
soluble Receptor Activator of NF-kappaB Ligand, TNFSF11, TRANCE (TNF-related activation-induced cytokine), OPGL, ODF (Osteoclast differentiation factor)
产品描述:
RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic cells. These dendritic cells then stimulate naive T-cell proliferation in a mixed lymphocyte reaction, promote the survival of RANK+ T-cells, and regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells, including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. Recombinant Rat sRANKL is a 19.4 kDa polypeptide comprising the TNF homologous region of RANKL (174 amino acid residues).
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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