Remdesivir-抑制剂-深圳欣博盛生物科技有限公司

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Remdesivir

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-3713-M005	规格：5 mg	目录价：￥720
货号：AG-CR1-3713-M025	规格：25 mg	目录价：￥2160
货号：AG-CR1-3713-M100	规格：100 mg	目录价：￥6480

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Remdesivir

别名:

GS-5734

产品描述:

Remdesivir is an adenosine triphosphate analog with broad-spectrum antiviral activity. It is a prodrug that metabolizes into its active form GS-441524 (Prod. No. AG-CR1-3722). GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of viral RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production (RNA synthesis arrest), either by terminating RNA chains or causing mutations. It inhibits MERS-CoV or SARS-CoV-infected HAE cultures (EC50=74nM and 69nM) and murine hepatitis virus (MHV) (EC50=30nM). In vivo, remdesivir (25 and 50 mg/kg) reduces lung viral titers and prevents weight loss in a mouse model of SARS-CoV infection. Remdesivir is used as a treatment for Ebola virus disease and Marburg virus infections, and other single stranded RNA viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, Nipah virus, Hendra virus and the coronaviruses (including MERS and SARS viruses). Remdesivir is effective in the control of 2019-nCoV (COVID-19) infection in vitro. It now also has been studied as potential treatment of SARS-CoV-2 infections.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

602.6

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.

产地:

瑞士