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折扣/货期| 货号：23845-1 mg | 规格：1 mg | 目录价：￥415 |
| 货号：23845-10 mg | 规格：10 mg | 目录价：￥2064 |
| 货号：23845-25 mg | 规格：25 mg | 目录价：￥3618 |
| 货号：23845-5 mg | 规格：5 mg | 目录价：￥1353 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Resmetirom
别名:
MGL-3196|VIA-3196
产品描述:
An agonist of TRβ (EC50s = 0.21 and 3.74 µM for TRβ and TRα, respectively); inhibits hERG channels (IC50 = 30 µM); liver-directed, with a liver to plasma ratio of 8:1 to reduce systemic exposure; does not affect the expression of α-MHC in a rat model of hypothyroidism, an effect mediated by TRα; lowers non-HDL cholesterol and liver triglycerides without affecting Tsh levels in rat and rabbit models of hypercholesterolemia; lowers plasma glucose levels and improves insulin sensitivity in DIO mice
保存温度:
-20
运输温度:
-20
预期分子量:
435.2
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
920509-32-6
分子式:
C17H12Cl2N6O4
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