| 货号:36806-1 mg | 规格:1 mg | 目录价:¥1260 |
| 货号:36806-10 mg | 规格:10 mg | 目录价:¥9943 |
| 货号:36806-25 mg | 规格:25 mg | 目录价:¥15531 |
| 货号:36806-5 mg | 规格:5 mg | 目录价:¥5601 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RG-7090
别名:
Basimglurant|RO4917523
产品描述:
A negative allosteric modulator of mGluR5; binds to mGluR5 (Ki = 35.6 nM); selective for mGluR5 over a panel of 116 additional receptors at 10 µM; inhibits quisqualate-induced calcium mobilization and inositol phosphate accumulation in HEK293 cells expressing human mGluR5 (IC50s = 7 and 5.9 nM, respectively); reduces immobility time in the forced swim test in rats at 10 and 30 mg/kg; has anxiolytic-like activity in rats; inhibits surgical sciatic nerve constriction-induced cold allodynia in rats at 0.1-10 mg/kg; increases the threshold of bladder filling volume to trigger the micturition reflex in anesthetized rats
保存温度:
-20
运输温度:
-20
预期分子量:
325.767143
产品形式:
A solid
纯度:
≥98%
CAS号:
802906-73-6
分子式:
C18H13ClFN3
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