深圳欣博盛生物科技有限公司 a1

RGX-104
货号:42120-10 mg 规格:10 mg 目录价:¥2626
货号:42120-25 mg 规格:25 mg 目录价:¥5119
货号:42120-5 mg 规格:5 mg 目录价:¥1461
货号:42120-50 mg 规格:50 mg 目录价:¥7303
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RGX-104
别名:
Abequolixron|SB-742881
产品描述:
An LXRa and LXRß agonist; induces recruitment of an SRC-1 fragment in cell-free FRET-based assays (EC50s = 74 and 25 nM for LXRa and LXRß, respectively); induces cholesterol efflux in RAW 264.7 macrophages (EC50 = 17 nM); increases plasma levels of VLDL, LDL, and triglycerides in hamsters at 10 mg/kg twice per day and decreases plasma levels of HDL in the same animals at 30 mg/kg twice per day; increases hepatic levels of triglycerides in hamsters at 10 or 30 mg/kg per day; increases serum levels of ApoB in cynomolgus monkeys at 10 mg/kg per day; decreases PHMG-induced increases in lung tissue levels of fibronectin and collagen 1A1 and BALF levels of foam macrophages in a mouse model of pulmonary fibrosis at 20 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
596.078669
产品形式:
A solid
纯度:
≥98%
CAS号:
610318-54-2
分子式:
C34H33ClF3NO3
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