Ribonuclease 3 Antibody / DROSHA / RNase III-多抗-深圳欣博盛生物科技有限公司

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Ribonuclease 3 Antibody / DROSHA / RNase III

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ5719

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Ribonuclease 3 Antibody / DROSHA / RNase III

产品描述:

Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

WB, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant human protein (amino acids E670-H903) was used as the immunogen for the Ribonuclease 3 antibody.

克隆性:

Polyclonal

纯化方式:

Affinity purified

保存温度:

After reconstitution, the Ribonuclease 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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