| 货号:24205-10 mg | 规格:10 mg | 目录价:¥1407 |
| 货号:24205-25 mg | 规格:25 mg | 目录价:¥3243 |
| 货号:24205-5 mg | 规格:5 mg | 目录价:¥911 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RN-1734
产品描述:
A TRPV4 antagonist (IC50s = 2.3, 5.9, and 3.2 µM for human, mouse, and rat, respectively), selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = >100, >30, and >30 µM, respectively), reduces GSK1016790A-induced increases in IGly from 34.5 to 0.97% in mouse hippocampal neurons in vitro (10 µM); blocks GSK1016790A-induced arteriolar dilation and increases myogenic tone in rat cremaster arterioles ex vivo (30 µM), reduces edema and MAPK signaling induced by traumatic brain injury in rats (1 mg/kg, i.p.), inhibits breakdown of the blood-retinal barrier in streptozotocin-induced diabetic rats (100 µM)
保存温度:
-20
运输温度:
-20
产品形式:
A 10 mg/ml solution in ethanol
纯度:
≥98%
CAS号:
946387-07-1
分子式:
C14H22Cl2N2O2S
促销活动
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官网链接
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