| 货号:AG-CR1-3515-M001 | 规格:1 mg | 目录价:¥360 |
| 货号:AG-CR1-3515-M005 | 规格:5 mg | 目录价:¥840 |
| 货号:AG-CR1-3515-M025 | 规格:25 mg | 目录价:¥2340 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RO-3306
别名:
(5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one
产品描述:
Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A) [1-3, 5]. Potential anti-cancer compound [1, 8]. Cell cycle arrest inducer at G1, S and G2/M [2, 7] . Apoptosis inducer in embryonic stem cells [4]. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines [6]. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387 [8, 9]. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards [9].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
351.5
产品形式:
solid
产地:
瑞士
纯度:
>95% (NMR)
CAS号:
872573-93-8
分子式:
C18H13N3OS2
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