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折扣/货期| 货号：29520-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：29520-5 mg | 规格：5 mg | 目录价：￥1273 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ro 60-0175
产品描述:
A 5-HT2 agonist; stimulates increases in intracellular calcium levels in CHO-K1 cells expressing human 5-HT2A, 5-HT2B, and 5-HT2C (EC50s = 447, 0.9, and 32 nM, respectively); selective for human 5-HT2A and 5-HT2C (Kis = 32 and 1 nM, respectively) over human 5-HT1A, 5-HT1D, 5-HT6, and 5-HT7, rat 5-HT1B and 5-HT3, and guinea pig 5-HT4 receptors (Kis = ≥1,995 nM), as well as adenosine A1 and A2, histamine H1-3, dopamine D1-5, α1-, α2-, and β1-adrenergic, M1-5 muscarinic, nicotinic, kainate, AMPA, and μ-, δ-, and κ-opioid receptors (IC50s = >1,000 nM), but does bind to β2-adrenergic receptors (IC50 = 251 nM); increases plasma levels of corticosterone, oxytocin, and prolactin in rats (ED50s = 2.43, 4.19, and 4.03 mg/kg, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
226.677563
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
169675-09-6
分子式:
C11H12ClFN2 • C4H4O4
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