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折扣/货期| 货号：25350-1 mg | 规格：1 mg | 目录价：￥4275 |
| 货号：25350-5 mg | 规格：5 mg | 目录价：￥11256 |
| 货号：25350-500 µg | 规格：500 µg | 目录价：￥2251 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
RO3244794
产品描述:
An IP receptor antagonist (Ki = 20 nM in isolated human platelets); selective for the IP receptor over a panel of 50 receptors at 10 µM but does bind to EP3, EP4, and TP receptors and the adenosine A3 receptor (Kis = 4,169, 1,820, 8,128, and 4,786 nM, respectively); inhibits carbaprostacyclin-induced cAMP accumulation in CHO-K1 cells expressing the human IP receptor (IC50 = 316 nM); prevents treprostinil-induced relaxation in U-46619-precontracted isolated rat pulmonary arteries at 1 µM; inhibits PGI2- or 12-HETrE-induced aggregation of isolated human platelet-rich plasma at 250 nM; decreases acetic-acid induced writhing and carrageenan-induced mechanical hyperalgesia and edema in rats; decreases the difference in weight distribution between the osteoarthritic and control hind paws in a rat model of sodium monoiodoacetate-induced osteoarthritis at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
451.418906
产品形式:
A solid
纯度:
≥98%
CAS号:
361457-01-4
分子式:
C25H19F2NO5
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