| 货号:19488-1 mg | 规格:1 mg | 目录价:¥871 |
| 货号:19488-10 mg | 规格:10 mg | 目录价:¥3926 |
| 货号:19488-25 mg | 规格:25 mg | 目录价:¥7611 |
| 货号:19488-5 mg | 规格:5 mg | 目录价:¥2613 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RO4987655
别名:
CH4987655
产品描述:
A MEK inhibitor (IC50 = 5 nM); selective for MEK over 400 kinases at 10 µM; inhibits proliferation of COLO 205, HT-29, QG56, MIA PaCa-2, and C32 cells (IC50s = 0.86, 1.7, 9.5, 3.3, and 8.4 nM, respectively); reduces tumor growth in a variety of mouse xenograft models; inhibits the phosphorylation of ERK in tumor tissue in an HT-29 mouse xenograft model at 6.25 mg/kg per day; acts synergistically with everolimus to reduce tumor volume in an HCT116 mouse xenograft model
保存温度:
-20
运输温度:
-20
预期分子量:
565.3
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
874101-00-5
分子式:
C20H19F3IN3O5
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