| 货号:32972-10 mg | 规格:10 mg | 目录价:¥1218 |
| 货号:32972-25 mg | 规格:25 mg | 目录价:¥2660 |
| 货号:32972-5 mg | 规格:5 mg | 目录价:¥686 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RO5166017
产品描述:
A TAAR1 agonist; binds to TAAR1 (Kis = 31, 24, 1.9, and 2.7 nM in HEK293 cells expressing the recombinant human, cynomolgus monkey, mouse, or rat enzyme, respectively) and is >15-fold selective for TAAR1 over a panel of 123 receptors, ion channels, and transporters at 10 µM; induces cAMP production in HEK293 cells expressing human, cynomolgus monkey, mouse, or rat TAAR1 (EC50s = 55, 97, 3.3, and 14 nM, respectively); reduces the frequency of neuronal firing in mouse VTA and DRN slices (IC50s = 1.73 and 2.99 nM, respectively); inhibits stress-induced hyperthermia, as well as reduces cocaine-induced hyperlocomotion, in mice; impairs expression of cocaine-induced place preference in rats
保存温度:
-20
运输温度:
-20
预期分子量:
219.283
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
1048346-74-2
分子式:
C12H17N3O
促销活动
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