RPA32 Antibody / RPA2-多抗-深圳欣博盛生物科技有限公司

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RPA32 Antibody / RPA2

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ5919

规格：100 ug

目录价：￥6488

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

RPA32 Antibody / RPA2

产品描述:

This gene encodes a subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The RPA complex protects single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which oligonucleotide/oligosaccharide-binding (OB) domains of the complex are utilized, and differing in the length of DNA bound. This subunit contains a single OB domain that participates in high-affinity DNA binding and also contains a winged helix domain at its carboxy terminus, which interacts with many genome maintenance protein. Post-translational modifications of the RPA complex also plays a role in co-ordinating different damage response pathways.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, IHC-P, IF, FACS, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant human protein (amino acids Q34-H254) was used as the immunogen for the RPA32 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Affinity purified

保存温度:

After reconstitution, the RPA32 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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