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折扣/货期| 货号：23451-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：23451-10 mg | 规格：10 mg | 目录价：￥2935 |
| 货号：23451-5 mg | 规格：5 mg | 目录价：￥1608 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
RS 127445 (hydrochloride)
产品描述:
A 5-HT2B receptor antagonist (Ki = 0.32 nM); selective for 5-HT2B over other 5-HT receptor subtypes (Ki = >3 μM for 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT3, 5-HT5, and 5-HT6); reduces contraction of rat isolated stomach fundus (pA2 = 9.5) and 5-HT-induced increases in intracellular calcium (IC50 = 0.04 nM); blocks (±)-α-methyl-5-HT-induced relaxation of isolated rat jugular veins (pA2 = 9.95); reduces peristaltic frequency and fecal output in mice in a dose-dependent manner; reduces basal, but not cocaine-induced, dopamine outflow in the nucleus accumbens of rats; decreases cocaine- or quinpirole-induced hyperlocomotion in rats
保存温度:
-20
运输温度:
-20
预期分子量:
281.327563
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
199864-86-3
分子式:
C17H16FN3 • HCl
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