官网链接
折扣/货期| 货号：F53890-0.05ML | 规格：0.05 ml | 目录价：￥2962 |
| 货号：F53890-0.2ML | 规格：0.2 ml | 目录价：￥6344 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
RSPO3 Antibody / R-spondin 3
产品描述:
R-spondin-3 is an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
免疫原:
A portion of amino acids 214-248 from the human protein was used as the immunogen for the RSPO3 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
Aliquot the RSPO3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Antigen affinity purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
促销活动
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