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折扣/货期| 货号：18870-10 mg | 规格：10 mg | 目录价：￥482.4 |
| 货号：18870-100 mg | 规格：100 mg | 目录价：￥3470.6 |
| 货号：18870-25 mg | 规格：25 mg | 目录价：￥1031.8 |
| 货号：18870-50 mg | 规格：50 mg | 目录价：￥1715.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Rufinamide
别名:
CGP 33101|RUF 331
产品描述:
An anticonvulsant; inhibits the activation of Nav1.1 at 100 µM; inhibits Nav1.1, but not Nav1.2, Nav1.3, and Nav1.6, opening and increases the action potential threshold in primary rat hippocampal neurons; inhibits CAVA (Ki = 343.8 nM) but not CAI and CAII (Kis = >10,000 nM for both); prolongs the preictal phase and reduces seizure-like event frequency in an in vitro model of epileptiform activity in rat hippocampal slices at 100 µM; inhibits pentylenetetrazole-induced seizures in a mouse model of epilepsy (ED50 = 54 mg/kg, i.p.); reduces kainic acid-induced neuronal cell death in the mouse hippocampal CA3 region when used at doses of 25, 50, and 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
238.2
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
106308-44-5
分子式:
C10H8F2N4O
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