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折扣/货期| 货号：23215-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：23215-10 mg | 规格：10 mg | 目录价：￥2935 |
| 货号：23215-25 mg | 规格：25 mg | 目录价：￥5628 |
| 货号：23215-5 mg | 规格：5 mg | 目录价：￥1715 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ruxolitinib (phosphate)
别名:
INC 424 (phosphate)|INCB 018424 (phosphate)
产品描述:
A potent ATP mimetic that inhibits JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively; less selective for JAK3 (IC50 = 322 nM); blocks IL-6 signaling (IC50 = 281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50 = 127 nM); reduces splenomegaly, decreases circulating levels of IL-6 and TNF-α, eliminates neoplastic cells, and prolongs survival in a mouse model of JAK2V617F+ MPN
保存温度:
-20
运输温度:
-20
预期分子量:
306.36526
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1092939-17-7
分子式:
C17H18N6 • H3PO4
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