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折扣/货期| 货号：27639-1 mg | 规格：1 mg | 目录价：￥1059 |
| 货号：27639-10 mg | 规格：10 mg | 目录价：￥6164 |
| 货号：27639-5 mg | 规格：5 mg | 目录价：￥4100 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
S 32212 (hydrochloride)
产品描述:
An inverse agonist of 5-HT receptor subtypes 5-HT2CINI and 5-HT2CVSV (Ki = 6.6 and 8.9 nM, respectively); an antagonist of the 5-HT2A receptor and the α2B-adrenergic receptors (Ki = 5.8 nM for both receptors); is greater than 70-fold selective for these receptors in a panel of 80 receptors, enzymes, and ion channels; reduces binding of GTPγS to Gαq and decreases the activity of PLC in HEK293 cells expressing 5-HT2CINI receptors (EC50s = 38 and 18.6 nM, respectively) and in CHO cells expressing 5-HT2CVSV receptors (EC50s = 38 and 18.6 nM, respectively); S 32212 (2.5 mg/kg) decreases head twitching, penile erections, and drug discrimination induced by 5-HT receptor agonists in mice and rats; reduces immobility in the forced swim test and decreases marble burying in mice and rats at 10 and 40 mg/kg, indicating anti-depressant-like and anxiolytic activities.
保存温度:
-20
运输温度:
-20
预期分子量:
416.51558
产品形式:
A solid
纯度:
≥98%
CAS号:
847871-78-7
分子式:
C25H28N4O2 • HCl
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