深圳欣博盛生物科技有限公司 a1

(S)-PHA-533533
货号:45337-1 mg 规格:1 mg 目录价:¥2519
货号:45337-10 mg 规格:10 mg 目录价:¥8630
货号:45337-5 mg 规格:5 mg 目录价:¥4971
货号:45337-500 µg 规格:500 µg 目录价:¥1327
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
(S)-PHA-533533
产品描述:
An inhibitor of Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk1/cyclin B complexes and GSK3β (IC50s = 37, 55, 65, 208, and 732 nM, respectively, in cell-free assays); selectively inhibits these complexes and GSK3β over Cdk4/cyclin D1 complex and a panel of 29 other kinases at 10 µM; inhibits the growth of A2780, HT-29, and HCT116 cells (IC50s = 744, 639, and 1,354 nM, respectively); induces cell cycle arrest at the G0/G1 phase in HT-29 cells; reduces tumor growth in an A2780 mouse xenograft model at 7.5 mg/kg; restores the expression of paternal UBE3A mRNA in a mouse model of Angelman syndrome
保存温度:
-20
运输温度:
-20
预期分子量:
338.411
产品形式:
A solid
纯度:
≥98%
CAS号:
437982-89-3
分子式:
C19H22N4O2
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