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折扣/货期| 货号：29248-1 mg | 规格：1 mg | 目录价：￥536 |
| 货号：29248-10 mg | 规格：10 mg | 目录价：￥3296 |
| 货号：29248-25 mg | 规格：25 mg | 目录价：￥7517 |
| 货号：29248-5 mg | 规格：5 mg | 目录价：￥1769 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SAR20347
产品描述:
A JAK family kinase inhibitor (IC50s = 0.6, 23, 26, and 41 nM, for TYK2 and JAK1-3, respectively, in cell-free assays); inhibits IL-12-induced TYK2-dependent phosphorylation of STAT4 in NK-92 cells (IC50 = 126 nM) and IL-6-induced JAK1-dependent phosphorylated STAT3 signaling in TF-1 cells (IC50 = 345 nM); inhibits IL-12-induced INF-γ production and reporter gene activity in PBMCs at 5 μM; inhibits the production of serum IFN-γ in mice at 60 mg/kg; reduces keratinocyte activation and skin levels of IL-12, IL-23, IL-6, IL-22 and IFN-γ in a mouse model of imiquimod-induced psoriasis
保存温度:
-20
运输温度:
-20
预期分子量:
444.843283
产品形式:
A solid
纯度:
≥98%
CAS号:
1450881-55-6
分子式:
C21H18ClFN4O4
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