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折扣/货期| 货号：40748-1 mg | 规格：1 mg | 目录价：￥1005 |
| 货号：40748-10 mg | 规格：10 mg | 目录价：￥5521 |
| 货号：40748-25 mg | 规格：25 mg | 目录价：￥8777 |
| 货号：40748-5 mg | 规格：5 mg | 目录价：￥3511 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SAR439859
别名:
Amcenestrant
产品描述:
A SERD; selectively induces degradation of ERα in MCF-7 cancer cells (EC50 = 0.2 nM) over ERβ, glucocorticoid, androgen, progesterone, and mineralocorticoid receptors at 5 µM but does activate ERβ signaling in reporter cells; decreases 17β-estradiol-induced proliferation of MCF-7 cells expressing wild-type ERα, MCF-7 cells expressing ERαY537S, and MCF-7 cells expressing ERαD538G (EC50s = 20, 331, and 595 nM, respectively); reduces tumor volume in a PDX mouse model of tamoxifen-resistant breast cancer
保存温度:
-20
运输温度:
-20
预期分子量:
554.478643
产品形式:
A solid
纯度:
≥98%
CAS号:
2114339-57-8
分子式:
C31H30Cl2FNO3
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