| 货号:41231-1 mg | 规格:1 mg | 目录价:¥1662 |
| 货号:41231-5 mg | 规格:5 mg | 目录价:¥6606 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SB-02024
产品描述:
An inhibitor of VPS34 (IC50 = 5 nM); selectively binds to VPS34 (Kd = 0.0011 µM) over eight other PI3K kinases (Kds = 1.2693->30 µM), mTOR (Kd = 1.0199 µM), a panel of 468 kinases at 1 µM, and an additional panel of 97 kinases at 1 µM; inhibits autophagic flux in H1299 cells at 0.7 µM; enhances increases in survival when used in combination with anti-PD-1 or -PD-L1 antibodies in B16/F10 murine melanoma and CT26 murine colorectal cancer models at 20 mg/kg; enhances increases in survival and decreases in tumor volume when used in combination with ADU-S100 in a B16/F10 murine melanoma model at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
345.360109
产品形式:
A solid
纯度:
≥98%
CAS号:
2126737-28-6
分子式:
C16H22F3N3O2
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