| 货号:42056-1 mg | 规格:1 mg | 目录价:¥375 |
| 货号:42056-10 mg | 规格:10 mg | 目录价:¥2211 |
| 货号:42056-25 mg | 规格:25 mg | 目录价:¥5079 |
| 货号:42056-5 mg | 规格:5 mg | 目录价:¥1394 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SB-505124 (hydrochloride)
别名:
TGF-β Receptor Type I Kinase Inhibitor III|TGF-β RI Kinase Inhibitor III
产品描述:
An ALK5 and ALK4 inhibitor (IC50s = 47 and 129 nM, respectively); selective for ALK5 and ALK4 over a panel of 27 kinases at 10 µM; inhibits ALK7-induced increases in phosphorylated SMAD2 levels in COS-1 cells overexpressing ALK7 at 5 µM; inhibits TGF-β-induced but not TNF-α-induced apoptosis in Fao cells at 1 µM; decreases IOP and subconjunctival immune cell infiltration in a rabbit model of trabeculectomy at 5 mg/eye
保存温度:
-20
运输温度:
-20
预期分子量:
335.39976
产品形式:
A solid
纯度:
≥98%
CAS号:
356559-13-2
分子式:
C20H21N3O2 • HCl
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