| 货号:39717-1 mg | 规格:1 mg | 目录价:¥375 |
| 货号:39717-10 mg | 规格:10 mg | 目录价:¥2948 |
| 货号:39717-5 mg | 规格:5 mg | 目录价:¥1675 |
| 货号:39717-50 mg | 规格:50 mg | 目录价:¥11055 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SC-13
别名:
FEN1 inhibitor SC-13|FEN1-IN-SC-13|Flap Endonuclease 1 Inhibitor SC-13|Flap Endonuclease 1-IN-SC-13
产品描述:
A FEN1 inhibitor and activator of STING (IC50 = 4.2 nM); increases the levels of γH2AX in MCF-7 and MDA-MB-231 cells at 40 µM; induces chromosomal aberrations in MCF-7 cells at 20 or 50 µM; potentiates the proliferation inhibition induced by cisplatin, 5-fluorouracil, or temozolomide in MCF-7 cells at 20 µM; increases levels of cGAS, phosphorylated STING, CCL5, and CCL10 in HeLa and MCF-7 cells at 20 µM; reduces tumor volume and weight without affecting body weight, as well as increases the number of CD8+ T cell tumor infiltrates, in combination with CAR-expressing T cells in a HeLa mouse xenograft model at 5 mg/kg every other day
保存温度:
-20
运输温度:
-20
预期分子量:
433.52384
产品形式:
A solid
纯度:
≥98%
CAS号:
2098776-03-3
分子式:
C24H23N3O3S
促销活动
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官网链接
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