| 货号:21552-1 mg | 规格:1 mg | 目录价:¥482 |
| 货号:21552-10 mg | 规格:10 mg | 目录价:¥3390 |
| 货号:21552-25 mg | 规格:25 mg | 目录价:¥7866 |
| 货号:21552-5 mg | 规格:5 mg | 目录价:¥2050 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SCH 529074
产品描述:
An activator of p53; restores DNA binding activity and increases DNA binding affinity of two recombinant GST fusion mutant p53 DNA binding domains (R273H and R249S) in an electrophoretic mobility shift assay (Kds = 0.6740 and 0.4313, respectively); stimulates DNA binding activity and prevents Hdm-2 ubiquitination of wild-type p53 in vitro; reduces proliferation of tumor cell lines with mutant and wild-type p53 (EC50s = 400-3,700 nM); reduces tumor growth in a DLD-1 human colorectal cancer xenograft model in mice in a dose-dependent manner
保存温度:
-20
运输温度:
-20
预期分子量:
563.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
922150-11-6
分子式:
C31H36Cl2N6
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