官网链接
折扣/货期| 货号：37754-10 mg | 规格：10 mg | 目录价：￥2734 |
| 货号：37754-25 mg | 规格：25 mg | 目录价：￥6445 |
| 货号：37754-5 mg | 规格：5 mg | 目录价：￥1434 |
| 货号：37754-50 mg | 规格：50 mg | 目录价：￥10733 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Seralutinib
别名:
GB002|PK 10571
产品描述:
A PDGFR, c-Kit, and CSF1R inhibitor; inhibits PDGF-BB-induced phosphorylation of ERK in H1703 cells, HPASMCs, and HLFs (IC50s = 74, 49, and 62 nM, respectively); inhibits stem cell factor-induced c-Kit autophosphorylation in HPAECs and M-CSF-induced CSF1R phosphorylation in human primary differentiated macrophages (IC50s = 7.8 and 14.4 nM, respectively); inhibits the proliferation of H1703 cells and PDGF-BB-induced HPASMCs and HLFs (IC50s = 32, 33, and 29 nM, respectively); prevents increases in pulmonary artery systolic pressure in a rat model of pulmonary arterial hypertension induced by monocrotaline pneumonectomy when administered via passive inhalation at 2.5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
469.53518
产品形式:
A solid
纯度:
≥98%
CAS号:
1619931-27-9
分子式:
C27H27N5O3
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