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折扣/货期| 货号：13967-10 mg | 规格：10 mg | 目录价：￥2693 |
| 货号：13967-25 mg | 规格：25 mg | 目录价：￥5601 |
| 货号：13967-5 mg | 规格：5 mg | 目录价：￥1420 |
| 货号：13967-50 mg | 规格：50 mg | 目录价：￥10492 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SGC0946
产品描述:
A DOT1L inhibitor (IC50 = 0.3 nM); selective for DOT1L over a panel of 12 additional protein methyltransferases, DNMT1, and a panel of 29 receptors and ion channels; reduces H3K79me2 levels in MCF-10A breast cancer cells (IC50 = 8.8 nM); selectively reduces the viability of isolated human cord blood cells transformed with an MLL-AF9 fusion oncogene over those transformed with a TLS-ERG fusion oncogene at 1 and 5 µM; adoptive transfer of isolated human CD3+ T cells pre-incubated with SGC0946 (0.5 µM) prevents weight loss, increases survival, and reduces hepatic and colonic lymphocyte infiltration in a xenogeneic mouse model GVHD
保存温度:
-20
运输温度:
-20
预期分子量:
618.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1561178-17-3
分子式:
C28H40BrN7O4
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