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折扣/货期| 货号：41170-1 mg | 规格：1 mg | 目录价：￥3269.6 |
| 货号：41170-10 mg | 规格：10 mg | 目录价：￥24441.6 |
| 货号：41170-5 mg | 规格：5 mg | 目录价：￥13038.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SGK3-PROTAC1
别名:
Serum/Glucocorticoid-regulated Kinase 3-PROTAC1|Serum/Glucocorticoid-regulated Kinase 3-Proteolysis-targeting Chimera 1|SGK3-Proteolysis-targeting Chimera 1
产品描述:
A PROTAC that drives SGK3 degradation; inhibits SGK3, SGK1, and S6K1 (IC50s = 0.3, 0.22, and 1.8 µM, respectively) but selectively induces degradation of SGK3 over SGK1 and S6K1 in HEK293 cells at 0.3-3 µM; potentiates GDC-0941-induced cell growth inhibition in CAMA-1 and ZR-75-1 breast cancer cells at 0.3 µM; reduces SGK3 levels, PiT-1 levels, and calcium deposition induced by high levels of Pi in primary mouse VSMCs at 2.5 µM
保存温度:
-20
运输温度:
-20
预期分子量:
1157.380723
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
2381320-35-8
分子式:
C57H73FN10O11S2
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