SHISA4 Antibody-多抗-深圳欣博盛生物科技有限公司

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SHISA4 Antibody

品牌：ProSci LLC

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说明书

折扣/货期

货号：7277-0.02 mg	规格：0.02 mg	目录价：￥1345.5
货号：7277-0.1 mg	规格：0.1 mg	目录价：￥6084

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SHISA4 Antibody

别名:

SHISA4 Antibody: TMEM58, C1orf40, TMEM58, UNQ583/PRO1153, Protein shisa-4, Transmembrane protein 58

反应种属:

Human,Mouse

宿主来源:

Rabbit

实验应用:

ELISA,WB,IHC-P,IF

靶标/特异性:

SHISA4 antibody is predicted to not cross-react with other SHISA protein family members.

同种型:

IgG

克隆性:

Polyclonal

纯化方式:

SHISA4 Antibody is affinity chromatography purified via peptide column.

偶联:

Unconjugated

产品浓度:

1 mg/mL

保存温度:

SHISA4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

SHISA4 Antibody is supplied in PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

SHISA4 Antibody: SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.

Accession #:

NP_937792

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