官网链接
折扣/货期| 货号：42724-1 mg | 规格：1 mg | 目录价：￥643 |
| 货号：42724-10 mg | 规格：10 mg | 目录价：￥5079 |
| 货号：42724-25 mg | 规格：25 mg | 目录价：￥7933 |
| 货号：42724-5 mg | 规格：5 mg | 目录价：￥2868 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SHR-0302
别名:
Ivarmacitinib
产品描述:
A JAK inhibitor (IC50s = 0.1, 0.9, and 7.7 nM for JAK1, -2, and -3, respectively); selective for these kinases over TYK2 (IC50 = 42 nM); inhibits the activation, proliferation, and TGF-β-1-induced migration of HSC-T6 cells from 0.1-10 µM; decreases collagen production and JAK1 and STAT3 phosphorylation in HSC-T6 cells; decreases disease severity and paw swelling in a rat model of adjuvant-induced arthritis at 3 mg/kg; increases survival, white blood cell count, red blood cell count, and platelet count and decreases body weight loss and disease severity in a mouse model of bone marrow transplant-induced GVHD when administered prophylactically at 5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
414.488
产品形式:
A solid
纯度:
≥95%
CAS号:
1445987-21-2
分子式:
C18H22N8O2S
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