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折扣/货期| 货号：9017P | 规格：0.05 mg | 目录价：￥1740.375 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SIGLEC15 Peptide
别名:
SIGLEC15 Antibody: CD33L3, HsT1361, SIGLEC-15, CD33L3, Sialic acid-binding Ig-like lectin 15, CD33 antigen-like 3, Siglec-15
实验应用:
Blocking
产品浓度:
200 ug/mL
保存温度:
Store SIGLEC15 Peptide at -20˚C, stable for one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
产地:
美国
生产商:
Prosci
功能与背景:
SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
Accession #:
NP_998767
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