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折扣/货期| 货号：32519-1 mg | 规格：1 mg | 目录价：￥656.6 |
| 货号：32519-10 mg | 规格：10 mg | 目录价：￥4408.6 |
| 货号：32519-5 mg | 规格：5 mg | 目录价：￥2854.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Simurosertib
别名:
TAK-931
产品描述:
An inhibitor of Cdc7 kinase (IC50 = 0.26 nM); selective for Cdc7 over Cdk2 and ROCK1 (IC50s = 6,300 and 430 nM, respectively); inhibits phosphorylation of MCM2 in HeLa cells (IC50 = 17 nM); reduces proliferation of COLO 205 cells (EC50 = 81 nM); inhibits the growth of a wide variety of cancer cells (GI50s = 30.2->10,000 nM); reduces intratumor levels of phosphorylated MCM2 in COLO 205 and SW948 mouse xenograft models at 80 mg/kg and reduces tumor growth in the same models when administered at doses of 40 or 60 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
341.43186
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1330782-76-7
分子式:
C17H19N5OS
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