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折扣/货期| 货号：29244-10 mg | 规格：10 mg | 目录价：￥1273 |
| 货号：29244-25 mg | 规格：25 mg | 目录价：￥2332 |
| 货号：29244-5 mg | 规格：5 mg | 目录价：￥670 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Sitaxentan (sodium salt)
别名:
TBC 11251|Thelin
产品描述:
A potent ETA receptor antagonist (IC50 = 1.4 nM); selective for ETA over ETB receptors (IC50 = 9,800 nM); inhibits endothelin-1-induced phosphoinositol hydrolysis in COS-7 cells (pA2 = 8); reduces blood pressure in a rat model of acute hypoxia-induced pulmonary hypertension (ED50 = 0.5 mg/kg); reduces femoral artery neointimal lesion size in a mouse model of intraluminal injury; decreases BALF pleocytosis, as well as pulmonary collagen deposition and fibrosis, and improves lung mechanics in a mouse model of bleomycin-induced lung injury at 15 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
453.89834
产品形式:
A solid
纯度:
≥95%
CAS号:
210421-74-2
分子式:
C18H14ClN2O6S2 • Na
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