| 货号:9003088-1 mg | 规格:1 mg | 目录价:¥402 |
| 货号:9003088-10 mg | 规格:10 mg | 目录价:¥3524.2 |
| 货号:9003088-25 mg | 规格:25 mg | 目录价:¥8334.8 |
| 货号:9003088-5 mg | 规格:5 mg | 目录价:¥1876 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SKA-121
产品描述:
A positive-gating modulator of IKCa1/KCa3.1 channels (EC50 = 109 nM); selective for KCa3.1 over KCa2.1, KCa2.2 and KCa2.3 (EC50s = 8,700, 6,800, and 4,400 nM, respectively), KCa1.1 as well as voltage-gated potassium and sodium channels; potentiates calcium-evoked KCa currents by approximately 7-fold (1 µM) as well as calcium-evoked and basal KCa currents; potentiates bradykinin-induced endothelium-dependent relaxation (EC50 = 7.9 nM) in large porcine coronary arteries ex vivo; lowers MAP ) by approximately 20 and 25 mm Hg in normo- and hypertensive mice (100 mg/kg)
保存温度:
-20
运输温度:
-20
预期分子量:
198.2
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1820708-73-3
分子式:
C12H10N2O
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