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折扣/货期| 货号：45614-1 mg | 规格：1 mg | 目录价：￥335 |
| 货号：45614-10 mg | 规格：10 mg | 目录价：￥2680 |
| 货号：45614-25 mg | 规格：25 mg | 目录价：￥5869.2 |
| 货号：45614-5 mg | 规格：5 mg | 目录价：￥1514.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SKLB03220
产品描述:
A covalent EZH2 inhibitor (IC50 = 1.72 nM); inhibits EZH2A677G, EZH2Y641N, and EZH2Y641F at 10 nM; selective for EZH2 over G9a, SUV39H1, SETD8, SMYD2, and PRMT1-7 at 10 µM but does inhibit EZH1 at 1 and 10 µM; selective for EZH2 over a panel of 224 kinases at 200 nM; inhibits the proliferation of PA-1 and A2780 ovarian cancer cells in a concentration-dependent manner; reduces H3K27Me3 levels and induces apoptosis in PA-1 cells; reduces tumor growth in a PA-1 mouse xenograft model at 75 and 150 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
556.707
产品形式:
A solid
纯度:
≥98%
CAS号:
2852050-29-2
分子式:
C33H40N4O4
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