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折扣/货期| 货号：21561-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：21561-10 mg | 规格：10 mg | 目录价：￥4060 |
| 货号：21561-25 mg | 规格：25 mg | 目录价：￥8429 |
| 货号：21561-5 mg | 规格：5 mg | 目录价：￥2144 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SKLB610
产品描述:
An inhibitor of VEGFR2; inhibits VEGFR2 activity by 97% but also inhibits FGFR2 and PDGFRβ activity by 65 and 55%, respectively, at 10 µM; selective for VEGFR2, FGFR2, and PDGFRβ over PI3K, EGFR, Aurora A, Cdk2/cyclin E, and Cdk6/cyclin D3 at 10 µM; inhibits VEGF- and bFGF-induced proliferation of HUVECs (IC50s = 2.2 and 4.7 µM, respectively); inhibits HUVEC capillary tube formation and migration at 2.5 and 10 µM, respectively; inhibits proliferation of a variety of cancer cells, including A549, HCT116, MDA-MB-231, Raji and DU145 cells (IC50s = 5.7, 5.3, 25.6, 6.4, and 6.3 µM, respectively); reduces tumor growth in A549 and HCT116 mouse xenograft models at 50 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
415.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1125780-41-7
分子式:
C21H16F3N3O3
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