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折扣/货期| 货号：AG-CR1-3503-M005 | 规格：5 mg | 目录价：￥1080 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SMI-4a
别名:
PIM1/2 Kinase Inhibitor V; (5E/Z)-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
产品描述:
Selective inhibitor of Pim-1 and Pim-2 protein kinases [1-5]. Inducer of G1 phase cell cycle arrest [1-5]. Inducer of p27Kip1 [1-5]. Inducer of apoptosis through the mitochondrial pathway [1-5]. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway [1-5]. Downregulates c-myc [1-5]. Inhibitor of PRAS40 phosphorylation and mTOR activity [1-5]. Potential anti-cancer compound [2,4,5]. Blocks prostate cancer growth [2,4,5]. Suppressor of cytokines production in lipopolysaccharide (LPS)-induced acute lung injury (ALI)
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
273.2
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (NMR)
CAS号:
327033-36-3
分子式:
C11H6F3NO2S
溶解度:
Soluble in DMSO (at least 5 mg/ml).
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