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折扣/货期| 货号：42960-1 mg | 规格：1 mg | 目录价：￥375 |
| 货号：42960-10 mg | 规格：10 mg | 目录价：￥3323 |
| 货号：42960-25 mg | 规格：25 mg | 目录价：￥7839 |
| 货号：42960-5 mg | 规格：5 mg | 目录价：￥1755 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SMI-6860766
产品描述:
An inhibitor of the TRAF6-CD40 protein-protein interaction; binds to TRAF1, TRAF2, TRAF3, and TRAF6 (Kds = 52, 30, 37, and 59 µM, respectively); inhibits LPS-induced increases in the levels of NF-κB in RAW 264.7 macrophages (IC50 = 0.3 µM); inhibits anti-Cd40 antibody-induced increases in the levels of Il-1β and Il-6 in primary mouse bone marrow-derived macrophages (BMDMs; IC50s = 5.7 and 2.4 µM, respectively); increases survival in a mouse model of sepsis induced by cecal ligation and puncture at 10 µmol/kg; decreases blood levels of glucose and adipose tissue levels of leukocytes, Ths, cytotoxic T cells, and M1 and M2 macrophages in a mouse model of DIO at 10 µmol/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
336.613
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
433234-16-3
分子式:
C15H11BrClNO
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