深圳欣博盛生物科技有限公司 a1

Sodium Butyrate
货号:13121-100 g 规格:100 g 目录价:¥670
货号:13121-250 g 规格:250 g 目录价:¥1541
货号:13121-50 g 规格:50 g 目录价:¥482
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Sodium Butyrate
别名:
Butyric Acid|FA 4:0
产品描述:
A short-chain fatty acid; produced predominately by bacterial fermentation of dietary fiber in the colon but has also been identified in mammalian milk; an HDAC inhibitor (IC50 = 90 µM in a cell-free assay); induces differentiation, cell cycle arrest at the G0 phase, and apoptosis, as well as inhibits proliferation, in a variety of cancer cells from 0.6-100 mM; decreases the expression of IFN-γ-related signaling genes and metastatic genes in H460 human lung cancer cells at 2 mM; reduces tumor growth in a CaSki mouse xenograft model at 200 and 800 mg/kg per day; reduces increases in colonic TNFa and Il6 expression and decreases colonic goblet cell depletion, tissue damage, muscle thickening, and cellular infiltration in a wild-type, but not Hcar2-/-, mouse model of TNBS-induced colitis
保存温度:
22
运输温度:
22
预期分子量:
110.1
产品形式:
A crystalline solid
纯度:
≥95%
来源:
Synthetic
CAS号:
156-54-7
分子式:
C4H7O2 • Na
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