深圳欣博盛生物科技有限公司 a1

Sorafenib
货号:10009644-10 mg 规格:10 mg 目录价:¥791
货号:10009644-25 mg 规格:25 mg 目录价:¥1822
货号:10009644-5 mg 规格:5 mg 目录价:¥523
货号:10009644-50 mg 规格:50 mg 目录价:¥3095
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Sorafenib
别名:
BAY 43-9006
产品描述:
A multi-kinase inhibitor; inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively); inhibits VEGFR2, VEGFR3, PDGFRβ, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively); selective for these kinases over 12 other kinases (IC50s = >10 µM for all); inhibits proliferation of PLC/PRF/5 and HepG2 cells (IC50s = 6.3 and 4.5 µM, respectively); inhibits tumor growth in a PLC/PRF/5 mouse xenograft model at 30 mg/kg; induces ferroptotic cell death in HT-1080 fibrosarcoma cells at 10 µM but not in a variety of other cancer cell lines; inhibits HCV replication in Huh7.5 cells (IC50 = 7.2 µM)
保存温度:
-20
运输温度:
-20
预期分子量:
464.8
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
284461-73-0
分子式:
C21H16ClF3N4O3
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