官网链接
折扣/货期| 货号：39158-10 mg | 规格：10 mg | 目录价：￥858 |
| 货号：39158-25 mg | 规格：25 mg | 目录价：￥1863 |
| 货号：39158-5 mg | 规格：5 mg | 目录价：￥536 |
| 货号：39158-50 mg | 规格：50 mg | 目录价：￥3444 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SR 4835
产品描述:
A Cdk12 and Cdk13 inhibitor; binds to Cdk12 and Cdk13 (Kds = 98 and 4.9 nM, respectively); inhibits Cdk12- and Cdk13-dependent phosphorylation of RNA polymerase II in MDA-MB-231 cells (EC50 = 105.5 nM); inhibits the proliferation of MDA-MB-231, MDA-MB-468, Hs 578T, and MDA-MB-436 breast cancer cells (EC50s = 15.5, 22.1, 19.9, and 24.9 nM, respectively); induces the DNA damage response and apoptosis in MDA-MB-231 from 30-90 nM; reduces tumor volume and decreases the number of mice with tumors greater than 1,000 mm3 in a PDX model of breast cancer at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
499.3557
产品形式:
A solid
纯度:
≥98%
CAS号:
2387704-62-1
分子式:
C21H20Cl2N10O
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询