Suramin . hexasodium salt-抑制剂-深圳欣博盛生物科技有限公司

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Suramin . hexasodium salt

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-3575-M050	规格：50 mg	目录价：￥840
货号：AG-CR1-3575-M250	规格：250 mg	目录价：￥3360

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Suramin . hexasodium salt

别名:

Germanin; NSC 34936; SK 24728

产品描述:

Potent ATPase inhibitor [1]. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity [2, 3]. Anticancer compound [4, 5, 15]. Protein kinase C (PKC) inhibitor [4]. Potent inhibitor of melanoma heparanase and tumor cell metastasis [6]. Non-specific growth factors inhibitor (including PDGF, EGF, aFGF and bFGF) [7, 16]. TGF-beta1 inhibitor [8]. Topoisomerase I and II inhibitor [9]. Interleukin-1 (IL-1) inhibitor [10]. Interleukin-4 (IL-4) inhibitor [11]. G protein inhibitor [12]. P2X and P2Y purinergic receptor antagonist [13]. Antiangiogenic. Potent VEGF inhibitor [14, 15]. Telomerase inhibitor [17]. Shows adjuvant properties [18]. Regulates ryanodine receptor [19]. Direct adenylyl cyclase inhibitor [20]. Protein synthesis inhibitor [21]. SIRT1 (sirtuin 1) and SIRT5 (sirtuin 5) inhibitor [22, 23]. Immunosuppressive [24]. Antifibrotic agent [25]. Antiparasitic. Antiprotozoal. Athelmintic [26]. Cullin-RING E3 ubiquitin ligase inhibitor [27]. Inhibitor of the STING pathway via the inhibition of cGAMP synthase (cGAS) enzymatic activity. Inhibits SARS-CoV-2 infection in cell culture by blocking early steps (binding/fusion) of the replication cycle. Potentially binds and inhibits nsp12 of SARS-CoV-2, binding to motifs harbouring the RNA-dependent RNA polymerases (RdRps) activity.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

1291.2 . 137.9

产品形式:

solid

产地:

瑞士