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折扣/货期| 货号：23459-10 mg | 规格：10 mg | 目录价：￥1675 |
| 货号：23459-25 mg | 规格：25 mg | 目录价：￥3229 |
| 货号：23459-5 mg | 规格：5 mg | 目录价：￥938 |
| 货号：23459-50 mg | 规格：50 mg | 目录价：￥5521 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SW044248
产品描述:
A DNA topoisomerase I inhibitor; exhibits selective cytotoxicity across a panel of 46 NSCLC lines (IC50s = ~2 μM for HCC4017, H292, and H1819 cells versus >20 μM for the remaining cell lines); induces cleavage of PARP and caspase-3 and blocks DNA replication, RNA transcription, and protein translation in susceptible-, but not resistant-, cells in a dose-dependent manner; inhibits the ability of recombinant topoisomerase 1 to relax supercoiled DNA; topoisomerase 1 knockdown rescues HCC4017 cells from SW04428 cytotoxicity; expression of CDKN1A reduces SW044248 cytotoxicity
保存温度:
-20
运输温度:
-20
预期分子量:
421.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
522650-83-5
分子式:
C22H23N5O2S
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