官网链接
折扣/货期| 货号：38494-1 mg | 规格：1 mg | 目录价：￥1139 |
| 货号：38494-5 mg | 规格：5 mg | 目录价：￥4516 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SZM-1209
产品描述:
A RIPK1 inhibitor; selectively binds to RIPK1 over RIPK3 (Kds = 85 and >10,000 nM, respectively); inhibits necrosome formation and phosphorylation of RIPK1 induced by TNF-α, SM-164, and Z-VAD-FMK in HT-29 cells (EC50 = 22.4 nM); decreases reductions in body temperature and improves survival in a mouse model of TNF-α- and Z-VAD-FMK-induced SIRS at 10 and 20 mg/kg; reduces lung RIPK1 phosphorylation, IL-6 and TNF-α levels, and total protein content, as well as decreases the number of hemorrhagic sites and congestion edema, in a mouse model of short-term intratracheal NNK exposure-induced ALI
保存温度:
-20
运输温度:
-20
预期分子量:
696.709936
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
2919801-86-6
分子式:
C31H29F5N4O5S2
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