深圳欣博盛生物科技有限公司 a1

T3-CLK
货号:41309-10 mg 规格:10 mg 目录价:¥3229
货号:41309-100 mg 规格:100 mg 目录价:¥18653
货号:41309-5 mg 规格:5 mg 目录价:¥1702
货号:41309-50 mg 规格:50 mg 目录价:¥13561
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
T3-CLK
别名:
CDC-like Kinase Inhibitor T3|CDC-like Kinase-IN-T3|CLK-IN-T3|T3-CDC-like Kinase
产品描述:
A pan-Clk inhibitor (IC50s = 0.67, 15, and 110 nM for Clk1, Clk2, and Clk3, respectively); selective for Clk1-3 over DYRK1A and DYRK1B (IC50s = 260 and 230 nM, respectively), as well as 62 kinases in a panel at 1,000 nM and four kinases in the same panel at 1,110 nM; reduces exon recognition and increases conjoined gene transcription in HCT116 colorectal cancer cells and 184-hTERT mammary epithelial cells; reduces VEGFR2 expression HUVECs at 300-1,000 nM; inhibits VEGF-induced-sprouting in HUVEC spheroids at 300 and 1,000 nM; inhibits HUVEC migration at 500, 800, and 1,000 nM
保存温度:
-20
运输温度:
-20
预期分子量:
482.57704
产品形式:
A solid
纯度:
≥98%
CAS号:
2109805-56-1
分子式:
C28H30N6O2
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