| 货号:29-312 | 规格:100 ul | 目录价:¥9108.45 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TAF15 Antibody
别名:
TAF15, Npl3, RBP56, TAF2N, TAFII68, hTAFII68
反应种属:
Human,Mouse
宿主来源:
Rabbit
实验应用:
ELISA,WB
克隆性:
Polyclonal
纯化方式:
Antibody is purified by peptide affinity chromatography method.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TAF15 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产地:
美国
生产商:
Prosci
功能与背景:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF15 encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.
Accession #:
NP_003478

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