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折扣/货期| 货号：13871-1 mg | 规格：1 mg | 目录价：￥1085 |
| 货号：13871-10 mg | 规格：10 mg | 目录价：￥5842 |
| 货号：13871-25 mg | 规格：25 mg | 目录价：￥11886 |
| 货号：13871-5 mg | 规格：5 mg | 目录价：￥3203 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TAK-242
别名:
Resatorvid
产品描述:
A TLR4 antagonist (IC50 = 0.68 µM in a SEAP assay); selectively binds to TLR4 over TLR1-3 and TLR5-10 at 100 nM; prevents the interaction of TLR4 with TIRAP or TRAM in HEK293 cells expressing the human receptors at 1 µM; inhibits IFN-γ- and LPS-induced production of NO, TNF-α, IL-6, and IL-1β in isolated mouse peritoneal macrophages (IC50s = 5.7-11 nM); inhibits LPS-induced NETosis in isolated human neutrophils at 5-20 µM; improves survival in a mouse model of LPS-induced septic shock at 0.3, 1, and 3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
361.8
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
243984-11-4
分子式:
C15H17NO4ClFS
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