| 货号:23772-1 mg | 规格:1 mg | 目录价:¥657 |
| 货号:23772-10 mg | 规格:10 mg | 目录价:¥5668 |
| 货号:23772-25 mg | 规格:25 mg | 目录价:¥12502 |
| 货号:23772-5 mg | 规格:5 mg | 目录价:¥2988 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TAK-901
产品描述:
A non-selective Aurora kinase inhibitor (IC50s = 3.1, 10, and 4.2 nM for Aurora A, B, and C, respectively); inhibits JAK3, c-Src, CLK2, FGR, YES1, LRRK2, FLT3, Fyn, Abl, and FGFR2 (IC50s = 1.2-6.4 nM); decreases histone H3 phosphorylation in human prostate PC3 cancer cells (EC50 = 0.16 μM) and inhibits c-Src, FAK, FGFR2, FLT3, Abl, and Axl autophosphorylation in a panel of cancer cell lines (EC50s = 0.19-3.7 μM); inhibits the growth of cancer cell lines (EC50s = 0.043-1.5 μM); inhibits histone H3 phosphorylation and reduces tumor growth in an A2780 ovarian cancer nude rat xenograft model (40 mg/kg per day, i.v.)
保存温度:
-20
运输温度:
-20
预期分子量:
504.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
934541-31-8
分子式:
C28H32N4O3S
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